Microchip-based device can detect rare tumor cells in bloodstream
A team of investigators from the Massachusetts General Hospital (MGH) BioMicroElectroMechanical Systems (BioMEMS) Resource Center and the MGH Cancer Center has developed a microchip-based device that...
View ArticleGene variation may elevate risk of liver tumor in patients with cirrhosis
A genetic variation appears to significantly increase the risk that individuals with cirrhosis of the liver will develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause...
View ArticleDrug based on MGH discovery may significantly improve treatment of dangerous...
Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder...
View ArticleMajor step forward in understanding cell reprogramming
Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like...
View ArticleNew strategy identified for improving effectiveness of cancer therapies
Manipulating levels of nitric oxide, a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of...
View ArticleHormone therapy for prostate cancer does not appear to increase cardiac deaths
Treating prostate cancer patients with drugs that block hormonal activity does not appear to increase the risk of death from cardiovascular disease, according to a study led by Harvard Medical School...
View ArticleAngiogenesis inhibitor improves brain tumor survival by reducing swelling
The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema – the swelling of brain tissue –...
View ArticleFirst molecular steps to childhood leukemia identified
A Harvard research based at Massachusetts General Hospital has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) – the most common cancer in...
View ArticleTreatment resistance in some cancer cells may be reversible
The ability of cancer cells to resist treatment with either targeted drug therapies or traditional chemotherapy may, in some cases, result from a transient state of reversible drug “tolerance.” In a...
View ArticleGene silencing may cause limitations of induced pluripotent stem cells
Scientists may be one step closer to being able to generate any type of cells and tissues from a patient’s own cells, according to the results of a new study by Harvard stem cell researchers at...
View ArticleWith fasting, enzyme turns off body’s production of fats, cholesterol
Fasting helps cause an enzyme with several important roles in energy metabolism to turn off the body’s generation of fats and cholesterol, Harvard researchers at Massachusetts General Hospital have...
View ArticleRare variants in gene coding may up risk of autoimmune disorders
Rare variants in the gene coding of an enzyme that controls the activity of a key immune cell occur more often in people with autoimmune disorders like rheumatoid arthritis and type 1 diabetes, Harvard...
View ArticleTargeting lung cancer
A small clinical trial of a potential targeted treatment drug has provided powerful evidence that it can halt or reverse the growth of lung tumors characterized by a specific genetic abnormality. In...
View ArticleCancer cells’ survival kit
Harvard-affiliated scientists at Dana-Farber Cancer Institute have discovered new details of how cancer cells escape from tumor suppression mechanisms that normally prevent these damaged cells from...
View ArticleMicrochip-based device can detect rare tumor cells in bloodstream
A team of investigators from the Massachusetts General Hospital (MGH) BioMicroElectroMechanical Systems (BioMEMS) Resource Center and the MGH Cancer Center has developed a microchip-based device that...
View ArticleGene variation may elevate risk of liver tumor in patients with cirrhosis
A genetic variation appears to significantly increase the risk that individuals with cirrhosis of the liver will develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause...
View ArticleDrug based on MGH discovery may significantly improve treatment of dangerous...
Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder...
View ArticleMajor step forward in understanding cell reprogramming
Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like...
View ArticleNew strategy identified for improving effectiveness of cancer therapies
Manipulating levels of nitric oxide, a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of...
View ArticleHormone therapy for prostate cancer does not appear to increase cardiac deaths
Treating prostate cancer patients with drugs that block hormonal activity does not appear to increase the risk of death from cardiovascular disease, according to a study led by Harvard Medical School...
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